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Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein
The potential of DNA vaccines has not been realised due to suboptimal delivery, poor antigen expression and the lack of localised inflammation, essential for antigen presentation and an effective immune response to the immunogen. Initially, we examined the delivery of a DNA vaccine encoding a model...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232068/ https://www.ncbi.nlm.nih.gov/pubmed/25505966 http://dx.doi.org/10.1038/cti.2014.13 |