Development of Stable Vibrio cholerae O1 Hikojima Type Vaccine Strains Co–Expressing the Inaba and Ogawa Lipopolysaccharide Antigens

We describe here the development of stable classical and El Tor V. cholerae O1 strains of the Hikojima serotype that co–express the Inaba and Ogawa antigens of O1 lipopolysaccharide (LPS). Mutation of the wbeT gene reduced LPS perosamine methylation and thereby gave only partial transformation into...

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Detalles Bibliográficos
Autores principales: Karlsson, Stefan L., Ax, Elisabeth, Nygren, Erik, Källgård, Susanne, Blomquist, Margareta, Ekman, Annelie, Benktander, John, Holmgren, Jan, Lebens, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232259/
https://www.ncbi.nlm.nih.gov/pubmed/25397871
http://dx.doi.org/10.1371/journal.pone.0108521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232259/
https://www.ncbi.nlm.nih.gov/pubmed/25397871
http://dx.doi.org/10.1371/journal.pone.0108521

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