Intranasal Administration of Human MSC for Ischemic Brain Injury in the Mouse: In Vitro and In Vivo Neuroregenerative Functions

Intranasal treatment with C57BL/6 MSCs reduces lesion volume and improves motor and cognitive behavior in the neonatal hypoxic-ischemic (HI) mouse model. In this study, we investigated the potential of human MSCs (hMSCs) to treat HI brain injury in the neonatal mouse. Assessing the regenerative capa...

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Detalles Bibliográficos
Autores principales: Donega, Vanessa, Nijboer, Cora H., Braccioli, Luca, Slaper-Cortenbach, Ineke, Kavelaars, Annemieke, van Bel, Frank, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232359/
https://www.ncbi.nlm.nih.gov/pubmed/25396420
http://dx.doi.org/10.1371/journal.pone.0112339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232359/
https://www.ncbi.nlm.nih.gov/pubmed/25396420
http://dx.doi.org/10.1371/journal.pone.0112339

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