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Promoter Methylation-Mediated Silencing of β-Catenin Enhances Invasiveness of Non-Small Cell Lung Cancer and Predicts Adverse Prognosis

β-Catenin plays dual role in adhesion complex formation and the Wnt signaling pathway. Although β-catenin expression appears to be upregulated and Wnt signaling pathway is activated in the majority of cancers, its expression level seems to be lost in non-small cell lung cancer (NSCLC). We previously...

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Detalles Bibliográficos
Autores principales: Miao, Yuan, Wang, Liang, Zhang, Xiupeng, Xu, Xiaohan, Jiang, Guiyang, Fan, Chuifeng, Liu, Yang, Lin, Xuyong, Yu, Juanhan, Zhang, Yong, Wang, Enhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232381/
https://www.ncbi.nlm.nih.gov/pubmed/25396757
http://dx.doi.org/10.1371/journal.pone.0112258