A Novel Simple Assay System to Quantify the Percent HCV-RNA Levels of NS5A Y93H Mutant Strains and Y93 Wild-Type Strains Relative to the Total HCV-RNA Levels to Determine the Indication for Antiviral Therapy with NS5A Inhibitors

AIM: Oral treatment with asunaprevir and daclatasvir has been reported to yield a SVR ratio of 80% in patients with genotype 1b HCV infection, however, treatment failure has been reported, especially in patients with HCV strains showing the NS5A-Y93H mutation at baseline. An assay system to detect s...

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Detalles Bibliográficos
Autores principales: Uchida, Yoshihito, Kouyama, Jun-ichi, Naiki, Kayoko, Mochida, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232421/
https://www.ncbi.nlm.nih.gov/pubmed/25397971
http://dx.doi.org/10.1371/journal.pone.0112647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232421/
https://www.ncbi.nlm.nih.gov/pubmed/25397971
http://dx.doi.org/10.1371/journal.pone.0112647

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