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Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling
Probes that form covalent bonds with RNA molecules based on their chemical reactivity would advance our ability to study the transcriptome. We developed a set of electrophilic activity-based RNA probes designed to react with unusually nucleophilic RNAs. We used these probes to identify reactive geno...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232462/ https://www.ncbi.nlm.nih.gov/pubmed/25306441 http://dx.doi.org/10.1038/nchembio.1655 |