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CRISPR/Cas9 Mediates Efficient Conditional Mutagenesis in Drosophila

Existing transgenic RNA interference (RNAi) methods greatly facilitate functional genome studies via controlled silencing of targeted mRNA in Drosophila. Although the RNAi approach is extremely powerful, concerns still linger about its low efficiency. Here, we developed a CRISPR/Cas9-mediated condit...

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Detalles Bibliográficos
Autores principales: Xue, Zhaoyu, Wu, Menghua, Wen, Kejia, Ren, Menda, Long, Li, Zhang, Xuedi, Gao, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232542/
https://www.ncbi.nlm.nih.gov/pubmed/25193494
http://dx.doi.org/10.1534/g3.114.014159