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Structures of Naturally Evolved CUP1 Tandem Arrays in Yeast Indicate That These Arrays Are Generated by Unequal Nonhomologous Recombination

An important issue in genome evolution is the mechanism by which tandem duplications are generated from single-copy genes. In the yeast Saccharomyces cerevisiae, most strains contain tandemly duplicated copies of CUP1, a gene that encodes a copper-binding metallothionein. By screening 101 natural is...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Strope, Pooja K., Kozmin, Stanislav G., McCusker, John H., Dietrich, Fred S., Kokoska, Robert J., Petes, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232551/
https://www.ncbi.nlm.nih.gov/pubmed/25236733
http://dx.doi.org/10.1534/g3.114.012922