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Structures of Naturally Evolved CUP1 Tandem Arrays in Yeast Indicate That These Arrays Are Generated by Unequal Nonhomologous Recombination
An important issue in genome evolution is the mechanism by which tandem duplications are generated from single-copy genes. In the yeast Saccharomyces cerevisiae, most strains contain tandemly duplicated copies of CUP1, a gene that encodes a copper-binding metallothionein. By screening 101 natural is...
Autores principales: | Zhao, Ying, Strope, Pooja K., Kozmin, Stanislav G., McCusker, John H., Dietrich, Fred S., Kokoska, Robert J., Petes, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232551/ https://www.ncbi.nlm.nih.gov/pubmed/25236733 http://dx.doi.org/10.1534/g3.114.012922 |
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