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Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2

We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosphate (PIP2). In this study we examined the cross-ta...

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Detalles Bibliográficos
Autores principales: Rosenhouse-Dantsker, Avia, Epshtein, Yulia, Levitan, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232564/
https://www.ncbi.nlm.nih.gov/pubmed/25408847
http://dx.doi.org/10.1016/j.csbj.2014.09.007