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Heart Mitochondrial Proteome Study Elucidates Changes in Cardiac Energy Metabolism and Antioxidant PRDX3 in Human Dilated Cardiomyopathy

BACKGROUND: Dilated cardiomyopathy (DCM) is a public health problem with no available curative treatment, and mitochondrial dysfunction plays a critical role in its development. The present study is the first to analyze the mitochondrial proteome in cardiac tissue of patients with DCM to identify po...

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Detalles Bibliográficos
Autores principales: Roselló-Lletí, Esther, Tarazón, Estefanía, Barderas, María G., Ortega, Ana, Otero, Manuel, Molina-Navarro, Maria Micaela, Lago, Francisca, González-Juanatey, Jose Ramón, Salvador, Antonio, Portolés, Manuel, Rivera, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232587/
https://www.ncbi.nlm.nih.gov/pubmed/25397948
http://dx.doi.org/10.1371/journal.pone.0112971