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Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing

In eukaryotes, intra-chromosomal recombination generates DNA circles, but little is known about how cells react to them. In yeast, partitioning of such circles to the mother cell at mitosis ensures their loss from the population but promotes replicative ageing. Nevertheless, the mechanisms of partit...

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Detalles Bibliográficos
Autores principales: Denoth-Lippuner, Annina, Krzyzanowski, Marek Konrad, Stober, Catherine, Barral, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232608/
https://www.ncbi.nlm.nih.gov/pubmed/25402830
http://dx.doi.org/10.7554/eLife.03790