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Research on the efficacy of Celastrus Orbiculatus in suppressing TGF-β1-induced epithelial-mesenchymal transition by inhibiting HSP27 and TNF-α-induced NF-κB/Snail signaling pathway in human gastric adenocarcinoma

BACKGROUND: Celastrus orbiculatus has been used as a folk medicine in China for the treatment of many diseases. In the laboratory, the ethyl acetate extract of Celastrus orbiculatus (COE) displays a wide range of anticancer functions. However, the inhibition of the metastasis mechanism of COE in gas...

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Detalles Bibliográficos
Autores principales: Zhu, Yaodong, Liu, Yanqing, Qian, Yayun, Dai, Xiaojun, Yang, Ling, Chen, Jue, Guo, Shiyu, Hisamitsu, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232669/
https://www.ncbi.nlm.nih.gov/pubmed/25370696
http://dx.doi.org/10.1186/1472-6882-14-433