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Lack of evidence of the interaction of the Aβ peptide with the Wnt signaling cascade in Drosophila models of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is the leading form of dementia worldwide. The Aβ-peptide is believed to be the major pathogenic compound of the disease. Since several years it is hypothesized that Aβ impacts the Wnt signaling cascade and therefore activation of this signaling pathway is propos...

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Detalles Bibliográficos
Autores principales: Lüchtenborg, Anne-Marie, Katanaev, Vladimir L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232725/
https://www.ncbi.nlm.nih.gov/pubmed/25387847
http://dx.doi.org/10.1186/s13041-014-0081-y