Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

Considerable progress has been made in generating fully functional and transplantable dopamine neurons from human embryonic stem cells (hESCs). Before these cells can be used for cell replacement therapy in Parkinson’s disease (PD), it is important to verify their functional properties and efficacy...

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Detalles Bibliográficos
Autores principales: Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Clinical Progress
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232736/
https://www.ncbi.nlm.nih.gov/pubmed/25517469
http://dx.doi.org/10.1016/j.stem.2014.09.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232736/
https://www.ncbi.nlm.nih.gov/pubmed/25517469
http://dx.doi.org/10.1016/j.stem.2014.09.017

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