A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by selective death of motor neurons. In 5–10% of the familial cases, the disease is inherited because of mutations. One such mutation, P56S, was identified in human VAPB that behaves in a dominant negative...

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Detalles Bibliográficos
Autores principales: Deivasigamani, Senthilkumar, Verma, Hemant Kumar, Ueda, Ryu, Ratnaparkhi, Anuradha, Ratnaparkhi, Girish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232771/
https://www.ncbi.nlm.nih.gov/pubmed/25361581
http://dx.doi.org/10.1242/bio.201410066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232771/
https://www.ncbi.nlm.nih.gov/pubmed/25361581
http://dx.doi.org/10.1242/bio.201410066

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