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A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder characterized by selective death of motor neurons. In 5–10% of the familial cases, the disease is inherited because of mutations. One such mutation, P56S, was identified in human VAPB that behaves in a dominant negative...
Autores principales: | Deivasigamani, Senthilkumar, Verma, Hemant Kumar, Ueda, Ryu, Ratnaparkhi, Anuradha, Ratnaparkhi, Girish S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232771/ https://www.ncbi.nlm.nih.gov/pubmed/25361581 http://dx.doi.org/10.1242/bio.201410066 |
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