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Econazole Nitrate Induces Apoptosis in MCF-7 Cells via Mitochondrial and Caspase Pathways

Econazole nitrate (EN), a synthetic compound, is now in use as a routine antifungal drug. EN was shown to have antitumor effect, the tumor cell killing mechanisms, however, remain unclear. In this research, the apoptosis-inducing effect of EN on MCF-7 cells was investigated. The results showed that...

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Detalles Bibliográficos
Autores principales: Sun, Juan, Yu, Chun-Hui, Zhao, Xue-Ling, Wang, Yang, Jiang, Shou-Gang, Gong, Xian-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232799/
https://www.ncbi.nlm.nih.gov/pubmed/25587322