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Night-time sedating H(1)-antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial

BACKGROUND: Many physicians believe that the most effective way to treat chronic urticaria is to take a nonsedating second-generation H(1)-antihistamine in the morning and a sedating first-generation H(1)-antihistamine, usually hydroxyzine, at night to enhance sleep. But is this belief well founded?...

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Detalles Bibliográficos
Autores principales: Staevska, M, Gugutkova, M, Lazarova, C, Kralimarkova, T, Dimitrov, V, Zuberbier, T, Church, MK, Popov, TA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232862/
https://www.ncbi.nlm.nih.gov/pubmed/24472058
http://dx.doi.org/10.1111/bjd.12846