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Scale-down characterization of post-centrifuge flocculation processes for high-throughput process development

Flocculation unit operations are being revisited as a strategy to ease the burden posed on clarification and purification operations by the increasingly high cell density cultures used in the biopharmaceutical industry. The purpose of this study was to determine the key process parameters impacting...

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Detalles Bibliográficos
Autores principales: Espuny Garcia del Real, Georgina, Davies, Jim, Bracewell, Daniel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232874/
https://www.ncbi.nlm.nih.gov/pubmed/24942244
http://dx.doi.org/10.1002/bit.25313