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Scale-down characterization of post-centrifuge flocculation processes for high-throughput process development
Flocculation unit operations are being revisited as a strategy to ease the burden posed on clarification and purification operations by the increasingly high cell density cultures used in the biopharmaceutical industry. The purpose of this study was to determine the key process parameters impacting...
Autores principales: | Espuny Garcia del Real, Georgina, Davies, Jim, Bracewell, Daniel G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232874/ https://www.ncbi.nlm.nih.gov/pubmed/24942244 http://dx.doi.org/10.1002/bit.25313 |
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