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Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV
BACKGROUND: Outcomes of neonates with herpes simplex virus (HSV) encephalitis are worse after infection with HSV-2 when compared with HSV-1. The proteins herpes virus entry mediator (HVEM) and nectin-1 mediate HSV entry into susceptible cells. Prior studies have shown receptor-dependent differences...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233006/ https://www.ncbi.nlm.nih.gov/pubmed/25198371 http://dx.doi.org/10.1038/pr.2014.135 |