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A miRNA upregulated in asthma airway T cells promotes T(H)2 cytokine production

MicroRNAs (miRNAs) exert powerful effects on immune function by tuning networks of target genes that orchestrate cell behavior. We sought to uncover miRNAs and miRNA-regulated pathways that control the T(H)2 responses that drive pathogenic inflammation in asthma. Profiling miRNA expression in human...

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Detalles Bibliográficos
Autores principales: Simpson, Laura J., Patel, Sana, Bhakta, Nirav R., Choy, David F., Brightbill, Hans D., Ren, Xin, Wang, Yanli, Pua, Heather H., Baumjohann, Dirk, Montoya, Misty M., Panduro, Marisella, Remedios, Kelly A., Huang, Xiaozhu, Fahy, John V., Arron, Joseph R., Woodruff, Prescott G., Ansel., Karl M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233009/
https://www.ncbi.nlm.nih.gov/pubmed/25362490
http://dx.doi.org/10.1038/ni.3026