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BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients

BACKGROUND: Mutations in KRAS, BRAF and PIK3CA are the most common somatic alterations found in the colorectal cancer (CRC) patients from Western countries; but their prevalence and prognostic value have not been adequately assessed in Asian patients. The aim of this study was to determine the mutat...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Guo, Fang, Shi, Xin, Zhang, Lihua, Zhang, Aifeng, Jin, Hui, He, Youji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233032/
https://www.ncbi.nlm.nih.gov/pubmed/25367198
http://dx.doi.org/10.1186/1471-2407-14-802