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PPARγ activation but not PPARγ haplodeficiency affects proangiogenic potential of endothelial cells and bone marrow-derived progenitors

BACKGROUND: Peroxisome proliferator-activated receptor-γ (PPARγ) agonists, which have been used as insulin sensitizers in diabetic patients, may improve functions of endothelial cells (ECs). We investigated the effect of PPARγ on angiogenic activities of murine ECs and bone marrow-derived proangioge...

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Detalles Bibliográficos
Autores principales: Kotlinowski, Jerzy, Grochot-Przeczek, Anna, Taha, Hevidar, Kozakowska, Magdalena, Pilecki, Bartosz, Skrzypek, Klaudia, Bartelik, Aleksandra, Derlacz, Rafal, Horrevoets, Anton J G, Pap, Attila, Nagy, Laszlo, Dulak, Jozef, Jozkowicz, Alicja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233236/
https://www.ncbi.nlm.nih.gov/pubmed/25361524
http://dx.doi.org/10.1186/s12933-014-0150-7