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Nuclear position dictates DNA repair pathway choice

Faithful DNA repair is essential to avoid chromosomal rearrangements and promote genome integrity. Nuclear organization has emerged as a key parameter in the formation of chromosomal translocations, yet little is known as to whether DNA repair can efficiently occur throughout the nucleus and whether...

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Detalles Bibliográficos
Autores principales: Lemaître, Charlène, Grabarz, Anastazja, Tsouroula, Katerina, Andronov, Leonid, Furst, Audrey, Pankotai, Tibor, Heyer, Vincent, Rogier, Mélanie, Attwood, Kathleen M., Kessler, Pascal, Dellaire, Graham, Klaholz, Bruno, Reina-San-Martin, Bernardo, Soutoglou, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233239/
https://www.ncbi.nlm.nih.gov/pubmed/25366693
http://dx.doi.org/10.1101/gad.248369.114