Role of DNA sequence in chromatin remodeling and the formation of nucleosome-free regions

AT-rich DNA is concentrated in the nucleosome-free regions (NFRs) associated with transcription start sites of most genes. We tested the hypothesis that AT-rich DNA engenders NFR formation by virtue of its rigidity and consequent exclusion of nucleosomes. We found that the AT-rich sequences present...

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Detalles Bibliográficos
Autores principales: Lorch, Yahli, Maier-Davis, Barbara, Kornberg, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233242/
https://www.ncbi.nlm.nih.gov/pubmed/25403179
http://dx.doi.org/10.1101/gad.250704.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233242/
https://www.ncbi.nlm.nih.gov/pubmed/25403179
http://dx.doi.org/10.1101/gad.250704.114

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