Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes

Eukaryotic RNAs with premature termination codons (PTCs) are eliminated by nonsense-mediated decay (NMD). While human nonsense RNA degradation can be initiated either by an endonucleolytic cleavage event near the PTC or through decapping, the individual contribution of these activities on endogenous...

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Detalles Bibliográficos
Autores principales: Lykke-Andersen, Søren, Chen, Yun, Ardal, Britt R., Lilje, Berit, Waage, Johannes, Sandelin, Albin, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233243/
https://www.ncbi.nlm.nih.gov/pubmed/25403180
http://dx.doi.org/10.1101/gad.246538.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233243/
https://www.ncbi.nlm.nih.gov/pubmed/25403180
http://dx.doi.org/10.1101/gad.246538.114

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