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miR-125b can enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survival
Previously, we identified miR-125b as a key regulator of the undifferentiated state of hair follicle stem cells. Here, we show that in both mice and humans, miR-125b is abundantly expressed, particularly at early stages of malignant progression to squamous cell carcinoma (SCC), the second most preva...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233245/ https://www.ncbi.nlm.nih.gov/pubmed/25403182 http://dx.doi.org/10.1101/gad.248377.114 |