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Multifunctional Core/Shell Nanoparticles Cross-linked Polyetherimide-folic Acid as Efficient Notch-1 siRNA Carrier for Targeted Killing of Breast Cancer

In gene therapy, how genetic therapeutics can be efficiently and safely delivered into target tissues/cells remains a major obstacle to overcome. To address this issue, nanoparticles consisting of non-covalently coupled polyethyleneimine (PEI) and folic acid (FA) to the magnetic and fluorescent core...

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Detalles Bibliográficos
Autores principales: Yang, Hong, Li, Ying, Li, Tingting, Xu, Min, Chen, Yin, Wu, Chunhui, Dang, Xitong, Liu, Yiyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233336/
https://www.ncbi.nlm.nih.gov/pubmed/25400232
http://dx.doi.org/10.1038/srep07072