Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers

We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon), allowing replication to be monitored and qu...

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Detalles Bibliográficos
Autores principales: Forrest, Sophie, Lear, Zoe, Herod, Morgan R., Ryan, Martin, Rowlands, David J., Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2014
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233629/
https://www.ncbi.nlm.nih.gov/pubmed/25096816
http://dx.doi.org/10.1099/vir.0.067751-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233629/
https://www.ncbi.nlm.nih.gov/pubmed/25096816
http://dx.doi.org/10.1099/vir.0.067751-0

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