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Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway

BACKGROUND: Recent studies have demonstrated a protective effect of osteocalcin (OCN) on glucose homeostasis and metabolic syndrome. However, its role in vascular function remains unknown. This study investigated the contribution of OCN to the pathogenesis of endothelial dysfunction in the thoracic...

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Detalles Bibliográficos
Autores principales: Dou, Jianxin, Li, Huating, Ma, Xiaojing, Zhang, Mingliang, Fang, Qichen, Nie, Meiyun, Bao, Yuqian, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233640/
https://www.ncbi.nlm.nih.gov/pubmed/24708830
http://dx.doi.org/10.1186/1475-2840-13-74