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Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway
BACKGROUND: Recent studies have demonstrated a protective effect of osteocalcin (OCN) on glucose homeostasis and metabolic syndrome. However, its role in vascular function remains unknown. This study investigated the contribution of OCN to the pathogenesis of endothelial dysfunction in the thoracic...
Autores principales: | Dou, Jianxin, Li, Huating, Ma, Xiaojing, Zhang, Mingliang, Fang, Qichen, Nie, Meiyun, Bao, Yuqian, Jia, Weiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233640/ https://www.ncbi.nlm.nih.gov/pubmed/24708830 http://dx.doi.org/10.1186/1475-2840-13-74 |
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