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Exact, time-independent estimation of clone size distributions in normal and mutated cells

Biological tools such as genetic lineage tracing, three-dimensional confocal microscopy and next-generation DNA sequencing are providing new ways to quantify the distribution of clones of normal and mutated cells. Understanding population-wide clone size distributions in vivo is complicated by multi...

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Detalles Bibliográficos
Autores principales: Roshan, A., Jones, P. H., Greenman, C. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233751/
https://www.ncbi.nlm.nih.gov/pubmed/25079870
http://dx.doi.org/10.1098/rsif.2014.0654