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Correlation between endogenous VWF:Ag and PK parameters and bleeding frequency in severe haemophilia A subjects during three-times-weekly prophylaxis with rFVIII-FS

Patients with severe haemophilia A experience frequent and spontaneous bleeding, causing debilitating damage to joints and decreasing quality of life. Prophylaxis with factor VIII (FVIII) reduces joint damage if initiated early. Circulating FVIII levels may be influenced by endogenous von Willebrand...

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Detalles Bibliográficos
Autores principales: Lalezari, S, Martinowitz, U, Windyga, J, Enriquez, M M, Delesen, H, Schwartz, L, Scharrer, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233978/
https://www.ncbi.nlm.nih.gov/pubmed/24252058
http://dx.doi.org/10.1111/hae.12294