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The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice

BACKGROUND: Allergen-specific immunotherapy favours immune deviation from a Th2 to a Th1 response and increases the number of regulatory T cells (Tregs). Epicutaneous immunotherapy (EPIT) of sensitized mice decreases the clinical and the allergen-specific Th2 responses and increases local and periph...

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Detalles Bibliográficos
Autores principales: Dioszeghy, V, Mondoulet, L, Dhelft, V, Ligouis, M, Puteaux, E, Dupont, C, Benhamou, P-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233996/
https://www.ncbi.nlm.nih.gov/pubmed/24666588
http://dx.doi.org/10.1111/cea.12312