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Association of BDNF Val66Met polymorphism with HPA and SAM axis reactivity to psychological and physical stress

BACKGROUND: Decreased expression of brain-derived neurotrophic factor (BDNF) is implicated in enhanced stress responses. The BDNF Val66Met polymorphism is associated with psychological changes; for example, carriers of the Met allele exhibit increased harm avoidance as well as a higher prevalence of...

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Detalles Bibliográficos
Autores principales: Tsuru, Jusen, Tanaka, Yoshihiro, Ishitobi, Yoshinobu, Maruyama, Yoshihiro, Inoue, Ayako, Kawano, Aimi, Ikeda, Rie, Ando, Tomoko, Oshita, Harumi, Aizawa, Saeko, Masuda, Koji, Higuma, Haruka, Kanehisa, Masayuki, Ninomiya, Taiga, Akiyoshi, Jotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234157/
https://www.ncbi.nlm.nih.gov/pubmed/25419135
http://dx.doi.org/10.2147/NDT.S68629