Structure-Based Evolution of Subtype-Selective Neurotensin Receptor Ligands

Subtype-selective agonists of the neurotensin receptor NTS2 represent a promising option for the treatment of neuropathic pain, as NTS2 is involved in the mediation of μ-opioid-independent anti-nociceptive effects. Based on the crystal structure of the subtype NTS1 and previous structure–activity re...

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Detalles Bibliográficos
Autores principales: Schaab, Carolin, Kling, Ralf Christian, Einsiedel, Jürgen, Hübner, Harald, Clark, Tim, Seebach, Dieter, Gmeiner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234217/
https://www.ncbi.nlm.nih.gov/pubmed/25478316
http://dx.doi.org/10.1002/open.201402031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234217/
https://www.ncbi.nlm.nih.gov/pubmed/25478316
http://dx.doi.org/10.1002/open.201402031

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