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Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery

BACKGROUND: CLIC4, a member of the CLIC family of proteins, was recently demonstrated to translocate to the nucleus in differentiating keratinocytes where it potentiates TGFβ-driven gene regulation. Since TGFβ signaling is known to play important roles in the fibrotic response to acute kidney injury...

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Detalles Bibliográficos
Autores principales: Edwards, John C, Bruno, Jonathan, Key, Phillip, Cheng, Yao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234247/
https://www.ncbi.nlm.nih.gov/pubmed/24708746
http://dx.doi.org/10.1186/1471-2369-15-54