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Absence of chloride intracellular channel 4 (CLIC4) predisposes to acute kidney injury but has minimal impact on recovery
BACKGROUND: CLIC4, a member of the CLIC family of proteins, was recently demonstrated to translocate to the nucleus in differentiating keratinocytes where it potentiates TGFβ-driven gene regulation. Since TGFβ signaling is known to play important roles in the fibrotic response to acute kidney injury...
Autores principales: | Edwards, John C, Bruno, Jonathan, Key, Phillip, Cheng, Yao-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234247/ https://www.ncbi.nlm.nih.gov/pubmed/24708746 http://dx.doi.org/10.1186/1471-2369-15-54 |
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