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Asymmetric distribution of phosphatidylserine is generated in the absence of phospholipid flippases in Saccharomyces cerevisiae

In eukaryotic cells, phosphatidylserine (PS) is predominantly located in the cytosolic leaflet of the plasma membrane; this asymmetry is generated by an unknown mechanism. In this study, we used the PS-specific probe mRFP-Lact-C2 to investigate the possible involvement of type 4 P-type ATPases, also...

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Detalles Bibliográficos
Autores principales: Mioka, Tetsuo, Fujimura-Kamada, Konomi, Tanaka, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234269/
https://www.ncbi.nlm.nih.gov/pubmed/25220349
http://dx.doi.org/10.1002/mbo3.211