cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells

BACKGROUND: The ataxia–telangiectasia mutated (ATM) protein kinase plays a central role in coordinating the cellular response to radiation-induced DNA damage. cAMP signaling regulates various cellular responses including metabolism and gene expression. This study aimed to investigate the mechanism t...

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Detalles Bibliográficos
Autores principales: Cho, Eun-Ah, Kim, Eui-Jun, Kwak, Sahng-June, Juhnn, Yong-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234305/
https://www.ncbi.nlm.nih.gov/pubmed/24568192
http://dx.doi.org/10.1186/1476-4598-13-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234305/
https://www.ncbi.nlm.nih.gov/pubmed/24568192
http://dx.doi.org/10.1186/1476-4598-13-36

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