Substitution of the Lys Linker with the β-Ala Linker Dramatically Decreased the Renal Uptake of (99m)Tc-Labeled Arg-X-Asp-Conjugated and X-Ala-Asp-Conjugated α-Melanocyte Stimulating Hormone Peptides

[Image: see text] The purpose of this study was to examine whether the substitution of the Lys linker with the β-Ala could reduce the renal uptake of (99m)Tc-labeled Arg-X-Asp-conjugated and X-Ala-Asp-conjugated α-melanocyte stimulating hormone (α-MSH) peptides. RSD-β-Ala-(Arg(11))CCMSH (1) {c[Arg-S...

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Detalles Bibliográficos
Autores principales: Flook, Adam M., Yang, Jianquan, Miao, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234429/
https://www.ncbi.nlm.nih.gov/pubmed/25290883
http://dx.doi.org/10.1021/jm501114v

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234429/
https://www.ncbi.nlm.nih.gov/pubmed/25290883
http://dx.doi.org/10.1021/jm501114v

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