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Discovery of Potent and Specific Dihydroisoxazole Inhibitors of Human Transglutaminase 2
[Image: see text] Transglutaminase 2 (TG2) is a ubiquitously expressed enzyme that catalyzes the posttranslational modification of glutamine residues on protein or peptide substrates. A growing body of literature has implicated aberrantly regulated activity of TG2 in the pathogenesis of various huma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234452/ https://www.ncbi.nlm.nih.gov/pubmed/25333388 http://dx.doi.org/10.1021/jm501145a |