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Tumor Induced Hepatic Myeloid Derived Suppressor Cells Can Cause Moderate Liver Damage

Subcutaneous tumors induce the accumulation of myeloid derived suppressor cells (MDSC) not only in blood and spleens, but also in livers of these animals. Unexpectedly, we observed a moderate increase in serum transaminases in mice with EL4 subcutaneous tumors, which prompted us to study the relatio...

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Detalles Bibliográficos
Autores principales: Eggert, Tobias, Medina-Echeverz, José, Kapanadze, Tamar, Kruhlak, Michael J., Korangy, Firouzeh, Greten, Tim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234460/
https://www.ncbi.nlm.nih.gov/pubmed/25401795
http://dx.doi.org/10.1371/journal.pone.0112717