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Implications of human genome structural heterogeneity: functionally related genes tend to reside in organizationally similar genomic regions

BACKGROUND: In an earlier study, we hypothesized that genomic segments with different sequence organization patterns (OPs) might display functional specificity despite their similar GC content. Here we tested this hypothesis by dividing the human genome into 100 kb segments, classifying these segmen...

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Detalles Bibliográficos
Autores principales: Paz, Arnon, Frenkel, Svetlana, Snir, Sagi, Kirzhner, Valery, Korol, Abraham B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234528/
https://www.ncbi.nlm.nih.gov/pubmed/24684786
http://dx.doi.org/10.1186/1471-2164-15-252