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Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10

β-cells in the pancreatic islet respond to elevated plasma glucose by secreting insulin to maintain glucose homeostasis. In addition to glucose stimulation, insulin secretion is modulated by numerous G-protein coupled receptors (GPCRs). The GPCR ligands Kisspeptin-10 (KP) and glucagon-like peptide-1...

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Detalles Bibliográficos
Autores principales: Schwetz, Tara A., Reissaus, Christopher A., Piston, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234631/
https://www.ncbi.nlm.nih.gov/pubmed/25401335
http://dx.doi.org/10.1371/journal.pone.0113020