Cargando…
Differential Stimulation of Insulin Secretion by GLP-1 and Kisspeptin-10
β-cells in the pancreatic islet respond to elevated plasma glucose by secreting insulin to maintain glucose homeostasis. In addition to glucose stimulation, insulin secretion is modulated by numerous G-protein coupled receptors (GPCRs). The GPCR ligands Kisspeptin-10 (KP) and glucagon-like peptide-1...
Autores principales: | Schwetz, Tara A., Reissaus, Christopher A., Piston, David W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234631/ https://www.ncbi.nlm.nih.gov/pubmed/25401335 http://dx.doi.org/10.1371/journal.pone.0113020 |
Ejemplares similares
-
Direct comparison of the effects of intravenous kisspeptin-10, kisspeptin-54 and GnRH on gonadotrophin secretion in healthy men
por: Jayasena, C.N., et al.
Publicado: (2015) -
Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals
por: Andreozzi, Francesco, et al.
Publicado: (2017) -
Systematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics
por: Tang, Jia-shu, et al.
Publicado: (2017) -
Effect of Endogenous GLP-1 on Insulin Secretion in Type 2 Diabetes
por: Salehi, Marzieh, et al.
Publicado: (2010) -
Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH
por: Gunawardana, Subhadra C, et al.
Publicado: (2004)