Mitochondrial Complex 1 Inhibition Increases 4-Repeat Isoform Tau by SRSF2 Upregulation

Progressive Supranuclear Palsy (PSP) is a neurodegenerative disorder characterised by intracellular aggregation of the microtubule-associated protein tau. The tau protein exists in 6 predominant isoforms. Depending on alternative splicing of exon 10, three of these isoforms have four microtubule-bin...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruch, Julius, Xu, Hong, De Andrade, Anderson, Höglinger, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234644/
https://www.ncbi.nlm.nih.gov/pubmed/25402454
http://dx.doi.org/10.1371/journal.pone.0113070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234644/
https://www.ncbi.nlm.nih.gov/pubmed/25402454
http://dx.doi.org/10.1371/journal.pone.0113070

Ejemplares similares