Cargando…
Upregulation of TPX2 by STAT3: Identification of a Novel STAT3 Binding Site
TPX2, a protein involved in mitosis, is considered a good marker for actively proliferating tissues, highly expressed in a number of cancer cells. We show the presence of high-affinity binding site for STAT3 in the 5′-flanking region of the Tpx2 gene, which is in vivo bound by activated STAT3. A spe...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234655/ https://www.ncbi.nlm.nih.gov/pubmed/25401333 http://dx.doi.org/10.1371/journal.pone.0113096 |